A scholarly academic publication is
typically a formal and professional publication written by researchers or
subject experts. The article that I chose for PB2A is titled "Alzheimer's
vaccine: a cure as dangerous as the disease?" and was written by G. Münch,
a researcher at University of Leipzig, and S. R. Robinson, a researcher at
Monash University. The title poses the question that drives the purpose of the
article: is the Alzheimer's vaccine, a supposed cure, as dangerous as the
disease itself?
The article is headed by the title of the
piece followed by the names of the authors and their credibility. The article
began with a brief summary of what was to be discussed in the full article and
provided the main points of the text. The summary informed that there were
studies done on transgenic mouse models that supposedly verified the potential
for this vaccine's development, but that once the vaccine was used on
Alzheimer's patients, the vaccine showed to negatively affect a small number of
its recipients with symptoms of brain inflammation. The summary was followed by
a short list of key words – “Alzheimer’s disease, vaccine, inflammation,
auto-immune disease” (1) –, which, assuming this is an online article would
make it easy for people to find this article is they are looking for an article
about any of the key words. Following the list of key words is the main body of
text in which the authors go in depth about how the studies conducted on the
transgenic mice suggested that the vaccine would be safe to use on humans and
would not cause any harmful side effects, but when some patients developed
unwanted side effects such as ventral nervous system inflammation, brain
inflammation, and meninoencephalitis, the use of the vaccine was temporarily
suspended. The article was then concluded with acknowledgements and references
that listed the authors’ sources of information.
Because this is a scholarly academic
publication, the authors use formal, professional language, and as this is a
research paper aimed toward the scientific, and more specifically the medical
community, the article is written with scientific jargon. The article is also
relatively brief – 4 paragraphs long – as it is meant to provide information
and educate its readers on the progression of this vaccine. The authors do not
include any unnecessary information or any information unrelated to the study
done on the vaccine or on how the vaccine was problematic.
The part of the article that seemed the
most important to me was the discussion of symptoms of brain inflammation that
affected certain patients, and the explanation of what could have caused the
brain inflammation to occur, as they address the main question that is posed in
the article and is the driving force for the article. Another reason I found
that part of the article important is because thee symptoms and side effects
related to the vaccine is that the vaccine are what affect the real life
patients of these trials. The article explained that the side effects that have
thus far affected the patients of the trial have been irreversible, and are
potentially life threatening. Even for people who are not apart of the
scientific community and do not participate in research for Alzheimer’s, it
should be important that more people be aware of life-threatening symptoms from
certain vaccines as to be wary of taking and vaccines or forms of medication
that could be dangerous.
As this is an article about a trial
vaccine that ultimately failed to serve its purpose, the last paragraph of the
text include ways in which scientists are trying to improve the vaccine as to
reduce and minimize the unwanted side effects produced by this vaccine. Most
research articles conclude with a statement about how researchers either have
found new advancements, or of how they are trying to improve their methods and
studies as to find new advancements.
Works Cited
Münch, G. and S. R. Robinson. “Alzheimer's vaccine: a cure as
dangerous as
the disease?”. Journal of Neural
Transmission, 2002. Print.




